Browsing by Author "Schröder, Martina"
Now showing items 1-2 of 2
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The human adaptor SARM negatively regulates adaptor protein TRIF–dependent Toll-like receptor signalling (Pre-published version)
Stack, Julianne; Carty, Michael; Goodbody, Rory; Schröder, Martina; Moynagh, Paul N.; Bowie, Andrew G. (Springer Nature, 2006)Toll-like receptors discriminate between different pathogen-associated molecules and activate signaling cascades that lead to immune responses. The specificity of Toll-like receptor signaling occurs by means of adaptor ... -
Vaccinia virus protein A46R targets multiple Toll-like–interleukin-1 receptor adaptors and contributes to virulence
Stack, Julianne; Haga, Ismar R.; Schröder, Martina; Bartlett, Nathan W.; Maloney, Geraldine; Reading, Patrick C.; Fitzgerald, Katherine A.; Smith, Geoffrey L.; Bowie, Andrew G. (The Rockefeller University Press, 2005)Viral immune evasion strategies target key aspects of the host antiviral response. Recently, it has been recognized that Toll-like receptors (TLRs) have a role in innate defense against viruses. Here, we define the function ...