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Now showing items 11-12 of 12
The TLR signaling adaptor TRAM interacts with TRAF6 to mediate activation of the inflammatory response by TLR4 (Pre-published version)
(John Wiley & Sons, 2014)
TLRs act as sentinels in professional immune cells to detect and initiate the innate immune response to pathogen challenge. TLR4 is a widely expressed TLR, responsible for initiating potent immune responses to LPS. TRAM ...
CS09-4. Molecular mechanism Of poxviral antagonism of the Tlr4 complex by vacv protein A46 (Pre-published version)
(Elsevier, 2011)
Toll like receptors (TLRs) are involved in the detection of viruses, leading to cytokine and interferon induction. TLR4, although best known for its role in recognising LPS, also plays a role in the immune response to ...