Browsing by Author "Jeon, Jannah"
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The TLR signaling adaptor TRAM interacts with TRAF6 to mediate activation of the inflammatory response by TLR4 (Pre-published version) Stack, Julianne; Verstak, Brett; Ve, Thomas; Mangan, Matthew; Hjerrild, Kathryn; Jeon, Jannah; Stahl, Rainer; Latz, Eicke; Gay, Nick; Kobe, Bostjan; Bowie, Andrew G.; Mansell, Ashley (John Wiley & Sons, 2014)TLRs act as sentinels in professional immune cells to detect and initiate the innate immune response to pathogen challenge. TLR4 is a widely expressed TLR, responsible for initiating potent immune responses to LPS. TRAM ...